SCHEMBL8466199

SCHEMBL8466199

CCCCOc1cc(C(=O)c2c(Cl)cccc2Cl)c(C)cc1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.45
PDE4A P27815 1/20 0.45
PDE4C Q08493 1/20 0.45
PDE4D Q08499 1/20 0.45
L3MBTL1 Q9Y468 5/20 0.43
HPGD P15428 4/20 0.43
MAPT P10636 4/20 0.42
RAB9A P51151 3/20 0.42
GAA P10253 1/20 0.42
NPC1 O15118 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SMPD1 P17405 3/20 0.41
RORC P51449 2/20 0.40
DPP4 P27487 1/20 0.40
MAPK1 P28482 1/20 0.40
CES2 O00748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8464014 0.96 SMPD1 (0.46) PDE4BPDE4APDE4CPDE4DL3MBTL1
SCHEMBL8465433 0.95 SMPD1 (0.47) PDE4BPDE4APDE4CPDE4DL3MBTL1
SCHEMBL8466653 0.95 SMPD1 (0.47) PDE4BPDE4APDE4CPDE4DL3MBTL1
SCHEMBL8463681 0.95 SMPD1 (0.47) PDE4BPDE4APDE4CPDE4DL3MBTL1
SCHEMBL8466704 0.95 SMPD1 (0.47) PDE4BPDE4APDE4CPDE4DL3MBTL1
SCHEMBL8463650 0.94 PDE4B (0.43) PDE4BPDE4APDE4CPDE4DL3MBTL1
SCHEMBL8463397 0.89 TSHR (0.45) L3MBTL1HPGDMAPTRAB9AGAA
SCHEMBL6150594 0.87 CES2 (0.48) PDE4DRAB9AGAANPC1CYP1A2
SCHEMBL9019424 0.87 PDE4B (0.44) PDE4BPDE4APDE4CPDE4DL3MBTL1
SCHEMBL8467299 0.86 HTT (0.41) L3MBTL1HPGDMAPTRAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727141-A2 Fungicidal methods, compounds and compositions containing benzophenones American Cyanamid Company (US) 1996-08-21 EP claimed
US-5922919-A Fungicidal methods, compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
US-5866722-A Fungicidal methods compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-02-02 US disclosed
US-5773663-A FOR CONTROL OF PHYTOPATHOGENIC FUNGI IN CROPS AMERICAN CYANAMID COMPANY (US) 1998-06-30 US disclosed
US-5679866-A CONTROLLING POWDERY MELDEW DISEASES AMERICAN CYANAMID COMPANY (US) 1997-10-21 US disclosed
EP-0727141-A2 Fungicidal methods, compounds and compositions containing benzophenones American Cyanamid Company (US) 1996-08-21 EP disclosed