SCHEMBL8466254

SCHEMBL8466254

Cc1cc(SCCC=C(F)F)on1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.32
VHL P40337 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026211 0.76 NOTUM (0.50) MEN1KMT2A
SCHEMBL7028283 0.72
SCHEMBL7022101 0.72 PTGS1 (0.30)
SCHEMBL7016919 0.72 CA12 (0.36) MEN1KMT2AALDH1A1
SCHEMBL8466022 0.71 MEN1 (0.34) MEN1KMT2A
SCHEMBL8466399 0.70
SCHEMBL7023241 0.68 NPC1 (0.32)
SCHEMBL7023155 0.68 SMN1; SMN2 (0.30)
SCHEMBL8462485 0.66 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7016228 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912243-A NOVEL COMPOUNDS FOR CONTROLLING NEMATODES, INSECT OR ACARID PESTS ZENECA LIMITED (GB) 1999-06-15 US disclosed