SCHEMBL846626

SCHEMBL846626

NCN[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL209664 0.72
SCHEMBL1313526 0.67
SCHEMBL9303276 0.67
SCHEMBL5473399 0.67
SCHEMBL1314335 0.65
SCHEMBL209481 0.65
SCHEMBL5255849 0.64 CA12 (0.43)
SCHEMBL5252546 0.64
SCHEMBL6985841 0.64 CA12 (0.43)
SCHEMBL9021234 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222456-B2 Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2012-07-17 US claimed
EP-2468711-A2 Facially amphiphilic polyaryl and polarylalkynyl polymers and oligomers and uses thereof The Trustees Of The University Of Pennsylvania (US) 2012-06-27 EP claimed
EP-1855704-A2 FACIALLY AMPHIPHILIC POLYMERS AND OLIGOMERS, COMPOSITIONS THEREOF, AND USE THEREOF IN METHODS OF TREATING CANCER The Trustees of The University of Pennsylvania (US) 2007-11-21 EP claimed
EP-1711455-A4 FACIALLY AMPHIPHILIC POLYARYL AND POLYARYLALKYNYL POLYMERS AND OLIGOMERS AND USES THEREOF UNIV PENNSYLVANIA (US) 2007-11-07 EP claimed
EP-1711455-A2 FACIALLY AMPHIPHILIC POLYARYL AND POLYARYLALKYNYL POLYMERS AND OLIGOMERS AND USES THEREOF The Trustees of The University of Pennsylvania (US) 2006-10-18 EP claimed
WO-2006093813-A2 FACIALLY AMPHIPHILIC POLYMERS AND OLIGOMERS, COMPOSITIONS THEREOF, AND USE THEREOF IN METHODS OF TREATING CANCER THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA et al. (US) 2006-09-08 WO claimed
US-20050287108-A1 Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof MIDCAP FINANCIAL SBIC, LP, AS ADMINISTRATIVE AGENT 2005-12-29 US claimed
WO-2005072246-A2 FACIALLY AMPHIPHILIC POLYARYL AND POLYARYLALKYNYL POLYMERS AND OLIGOMERS AND USES THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2005-08-11 WO claimed
WO-2024043651-A1 PEPTIDE FOR IMPROVING SOLUBILITY, AND COMPOSITION FOR IMPROVING SOLUBILITY COMPRISING SAME ㈜에빅스젠 2024-02-29 WO disclosed
US-20210093636-A1 Arylamide compounds and compositions and uses thereof INNOVATION PHARMACEUTICALS INC. 2021-04-01 US disclosed
US-10166232-B2 Arylamide compounds and compositions and uses thereof INNOVATION PHARMACEUTICALS INC. (US) 2019-01-01 US disclosed
US-20160228435-A1 Arylamide compounds and compositions and uses thereof INNOVATION PHARMACEUTICALS INC. 2016-08-11 US disclosed
US-9192623-B2 Arylamide compounds and compositions and uses thereof CELLCEUTIX CORPORATION (US) 2015-11-24 US disclosed
US-8809538-B2 Piperidine-containing compounds and use thereof ARRAY BIOPHARMA INC. (US) 2014-08-19 US disclosed
WO-1998056771-A2 PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1998-12-17 WO disclosed
EP-0765314-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-02 EP disclosed
WO-1995034540-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-12-21 WO disclosed
EP-0102062-B1 1,3-DITHIANES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1988-11-23 EP disclosed
US-4640929-A Insecticidally, acaricidally, and nematocidally 2-amino-1,3-dithiane derivatives and pesticidal compositions therefor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-02-03 US disclosed
EP-0102062-A2 1,3-Dithianes, their production and use Takeda Chemical Industries, Ltd. (JP) 1984-03-07 EP disclosed