Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467616 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL9828390 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7771209 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7765623 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7769016 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7770755 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7770749 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7769533 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7770760 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA | |
| SCHEMBL7770751 | 0.98 | PLA2G2A (0.56) | SMN1; SMN2PLA2G2APLA2G5PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |