Bromoxynil

Bromoxynil

SCHEMBL8466645

N#Cc1cc(Br)c(O)c(Br)c1.N#Cc1cc(I)c(O)c(I)c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.76
ALB P02768 2/20 0.76
MEN1 O00255 2/20 0.76
KMT2A Q03164 2/20 0.76
CHEK1 O14757 1/20 0.44
DAPK3 O43293 1/20 0.44
RET P07949 1/20 0.44
PDGFRB P09619 1/20 0.44
PIM1 P11309 1/20 0.44
PDGFRA P16234 1/20 0.44
KDR P35968 1/20 0.44
MAPK8 P45983 1/20 0.44
RPS6KA3 P51812 1/20 0.44
LIMK1 P53667 1/20 0.44
TYRO3 Q06418 1/20 0.44
MAPK14 Q16539 1/20 0.44
LRRK2 Q5S007 1/20 0.44
AURKB Q96GD4 1/20 0.44
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromoxynil SCHEMBL1701902 0.87 TTR (1.00) TTRALBMEN1KMT2ACYP3A4
Ioxynil SCHEMBL39616 0.87 TTR (1.00) TTRALBMEN1KMT2ACHEK1
Bromoxynil SCHEMBL19210 0.87 TTR (1.00) TTRALBMEN1KMT2ACYP3A4
Ioxynil SCHEMBL1701373 0.87 TTR (1.00) TTRALBMEN1KMT2ACHEK1
Bromoxynil SCHEMBL29642876 0.85 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL466353 0.85 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL726301 0.85 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL22721314 0.85 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Ioxynil SCHEMBL3687268 0.85 TTR (0.95) TTRALBMEN1KMT2ACHEK1
Ioxynil SCHEMBL8211431 0.85 TTR (0.95) TTRALBMEN1KMT2ACHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0491916-B1 WATER DISPERSIBLE GEL FORMULATIONS RHONE POULENC AGROCHIMIE (FR) 1999-09-22 EP disclosed
US-5877115-A POSTEMERGENCE HERBICIDE SANDOZ LTD. (CH) 1999-03-02 US disclosed
US-5021083-A Stable aqueous or aqueous alcoholic dispersion based on derivatives of oxynil, herbicidal composition comprised thereof and selective herbicidal treatment comprising the use of the said herbicidal composition COMPAGNIE FRANCAISE DE PRODUITS INDUSTRIELS (FR) 1991-06-04 US disclosed
EP-0120578-A2 Herbicidal compositions and their use to control undesirable weeds ROHM AND HAAS FRANCE, S.A. (FR) 1984-10-03 EP disclosed