Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.52 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467138 | 0.98 | ADORA2A (0.60) | ADORA2AADORA1FDPSADCY1P2RX7 | |
| SCHEMBL8464071 | 0.98 | ADORA2A (0.60) | ADORA2AADORA1FDPSADCY1P2RX7 | |
| SCHEMBL11596726 | 0.95 | ADORA2A (0.68) | ADORA2AADORA1FDPSADCY1P2RX7 | |
| SCHEMBL9741153 | 0.89 | ADORA2A (0.66) | ADORA2AADORA1FDPSADCY1P2RX7 | |
| SCHEMBL2001378 | 0.87 | FDPS (0.51) | ADORA2AADORA1FDPSP2RX7HDAC6 | |
| SCHEMBL11597661 | 0.86 | FDPS (0.50) | ADORA2AADORA1FDPSP2RX7HDAC6 | |
| SCHEMBL11596860 | 0.85 | FDPS (0.52) | ADORA2AADORA1FDPSP2RX7HDAC6 | |
| SCHEMBL10589823 | 0.84 | ADORA2A (0.61) | ADORA2AADORA1FDPSP2RX7HDAC6 | |
| SCHEMBL6061412 | 0.84 | FDPS (0.49) | ADORA2AADORA1FDPSP2RX7HDAC6 | |
| SCHEMBL11899180 | 0.83 | ADORA2A (0.60) | ADORA2AADORA1FDPSP2RX7HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |
| US-4100286-A | 2-(Substituted heterocyclic amine)benzoic acids | SCIENCE UNION ET CIE (FR) | 1978-07-11 | — | — | US | disclosed |