Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21346945 | 0.84 | CYP1A2 (0.47) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL8165697 | 0.79 | CYP1A2 (0.57) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL27526995 | 0.77 | CYP1A2 (0.55) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL8759255 | 0.77 | GAA (0.44) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL18642720 | 0.76 | CYP1A2 (0.59) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL29750121 | 0.76 | CYP1A2 (0.53) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL16358138 | 0.76 | CYP1A2 (0.53) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL5503646 | 0.75 | CYP1A2 (0.48) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL6975752 | 0.75 | CYP1A2 (0.48) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL23544374 | 0.74 | TSHR (0.49) | CYP1A2TSHRALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5964919-A | STABILIZING THE ACTIVE ZINC BY SUSPENDING IN A CONTAINER WITH AN SOLVENT SELECT FROM ETHER, HYDROCARBON, AROMATIC HYDROCARABON OR APROTIC SOLVENT UNDER INERT GAS, SEALING THE CONTAINER | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1999-10-12 | — | — | US | disclosed |
| US-5756653-A | REACTING A REDUCING AGENT ON A ZINC SALT | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1998-05-26 | — | — | US | disclosed |
| US-5358546-A | Reacting a zinc compound with a reducting agent | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1993015086-A1 | HIGHLY REACTIVE FORMS OF ZINC AND REAGENTS THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-08-05 | — | — | WO | disclosed |