Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | ADA | P00813 | 1/20 | 0.41 |
| ▸ | NPEPPS | P55786 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 6/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18410860 | 0.83 | MAPK1 (0.60) | MAPK1CYP1A2CYP2D6HIF1AADA | |
| SCHEMBL25926228 | 0.81 | NPEPPS (0.45) | MAPK1CYP1A2CYP2D6HIF1ANPEPPS | |
| SCHEMBL18410785 | 0.79 | SLC29A1 (0.52) | MAPK1CYP1A2CYP2D6HIF1ANPEPPS | |
| SCHEMBL8617607 | 0.78 | NPEPPS (0.44) | MAPK1CYP1A2CYP2D6HIF1ANPEPPS | |
| SCHEMBL8617599 | 0.78 | NPEPPS (0.44) | MAPK1CYP1A2CYP2D6HIF1ANPEPPS | |
| SCHEMBL1997331 | 0.77 | HIF1A (0.71) | HIF1ALMNASMN1; SMN2TP53 | |
| SCHEMBL6270350 | 0.77 | HIF1A (0.71) | HIF1ALMNASMN1; SMN2TP53 | |
| SCHEMBL9707007 | 0.77 | CYP1A2 (0.44) | MAPK1CYP1A2CYP2D6HIF1ANPEPPS | |
| SCHEMBL26647541 | 0.77 | HIF1A (0.71) | HIF1ALMNASMN1; SMN2TP53 | |
| SCHEMBL6270353 | 0.77 | HIF1A (0.71) | HIF1ALMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |