Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.52 |
| ▸ | S100A4 | P26447 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464969 | 0.95 | HSP90AA1 (0.56) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL8465216 | 0.80 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465385 | 0.80 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465085 | 0.80 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1 | |
| SCHEMBL8143919 | 0.80 | HSP90AA1 (0.57) | PTPRCS100A4HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL8465017 | 0.76 | HSP90AA1 (0.56) | PTPRCS100A4HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL8466610 | 0.74 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465304 | 0.74 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL8156872 | 0.74 | HSP90AA1 (0.61) | PTPRCS100A4HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL8464981 | 0.71 | HSP90AA1 (0.63) | PTPRCS100A4HSP90AA1HSP90AB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981544-A | Mono-- or diketone tetracyclic derivatives and therapeutical uses thereof | LABORATOIRE INNOTHERA (FR) | 1999-11-09 | — | — | US | disclosed |