Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 5/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27138382 | 0.78 | — | — | |
| Aniline SCHEMBL10614149 | 0.76 | TSHR (0.41) | TSHRTDP1MAOAMAOBGAA | |
| Ethylamine SCHEMBL2156709 | 0.74 | — | — | |
| Aniline SCHEMBL14801950 | 0.72 | TSHR (0.50) | TSHRTDP1MAOAMAOBMAPT | |
| Aniline SCHEMBL28340356 | 0.69 | TSHR (0.58) | TSHRTDP1MAOAMAOBTAAR1 | |
| SCHEMBL27582618 | 0.69 | SLC6A2 (0.37) | TSHRTDP1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL16144804 | 0.69 | SLC6A2 (0.46) | TSHRSMN1; SMN2TAAR1SLC6A2 | |
| Aniline SCHEMBL6154453 | 0.68 | TSHR (0.73) | TSHRTDP1MAOAMAOBMAPT | |
| Aniline SCHEMBL28119117 | 0.68 | TSHR (0.73) | TSHRTDP1MAOAMAOBMAPT | |
| Aniline SCHEMBL17710399 | 0.68 | TSHR (0.55) | TSHRTDP1MAOAMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676403-B1 | Arylaminosilane end-capped urethane sealants | WITCO CORP (US) | 1999-09-15 | — | — | EP | claimed |
| EP-0676403-A1 | Arylaminosilane end-capped urethane sealants | OSI SPECIALTIES, INC. (US) | 1995-10-11 | — | — | EP | claimed |
| EP-0676403-B1 | Arylaminosilane end-capped urethane sealants | WITCO CORP (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0676403-A1 | Arylaminosilane end-capped urethane sealants | OSI SPECIALTIES, INC. (US) | 1995-10-11 | — | — | EP | disclosed |