SCHEMBL8467229

SCHEMBL8467229

OCCC1CCC(S)CC1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.42
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5733 0.85
SCHEMBL24197652 0.85 ESR2 (0.50) ESR2BRD4
SCHEMBL240852 0.85 ESR2 (0.50) ESR2BRD4
SCHEMBL8465348 0.84
SCHEMBL21417726 0.82
SCHEMBL15842184 0.77 ESR2 (0.53) ESR2BRD4
SCHEMBL12186323 0.77
SCHEMBL21110513 0.77 ESR2 (0.45) ESR2BRD4
SCHEMBL899402 0.77 ESR2 (0.45) ESR2BRD4
SCHEMBL760537 0.77 ESR2 (0.45) ESR2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869471-A Methods for the treatment of arthritis using phosphonates and NSAIDS THE PROCTOR & GAMBLE COMPANY (US) 1999-02-09 US disclosed
US-5824661-A TREATMENT OF OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS THE PROCTER & GAMBLE COMPANY (US) 1998-10-20 US disclosed