SCHEMBL8467252

SCHEMBL8467252

CCN(CC)c1ccc(N)cc1.CCN(CC)c1ccc(N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 1.00
L3MBTL1 Q9Y468 5/20 1.00
CYP3A4 P08684 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
MAPK1 P28482 2/20 1.00
TSHR P16473 2/20 1.00
GFER P55789 2/20 1.00
PSMD14 O00487 1/20 1.00
RECQL P46063 1/20 1.00
ALDH3A1 P30838 1/20 0.54
ALDH1A3 P47895 1/20 0.54
S100B P04271 1/20 0.54
TP53 P04637 1/20 0.52
ALOX15 P16050 1/20 0.52
ESRRG P62508 1/20 0.49
KDM4E B2RXH2 4/20 0.48
MAPT P10636 4/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33781 1.00 ALDH1A1 (1.00) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
Hydrochloric Acid SCHEMBL970320 0.97 ALDH1A1 (0.95) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
Hydrochloric Acid SCHEMBL970321 0.97 ALDH1A1 (0.95) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
Hydrochloric Acid SCHEMBL7752117 0.95 ALDH1A1 (0.91) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
Potassium Iodide SCHEMBL28933576 0.93 ALDH1A1 (0.86) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
Iodide SCHEMBL5069469 0.93 ALDH1A1 (0.86) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
SCHEMBL2155334 0.93 ALDH1A1 (0.86) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
Sulfur Dioxide SCHEMBL6515046 0.91 ALDH1A1 (0.83) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
SCHEMBL8715756 0.91 ALDH1A1 (0.83) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1
SCHEMBL29740663 0.90 ALDH1A1 (0.82) ALDH1A1L3MBTL1CYP3A4TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US disclosed