Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15157568 | 1.00 | GAA (0.38) | GAATSHRKDM4ETDP1ALDH1A1 | |
| SCHEMBL9617553 | 0.93 | GAA (0.36) | GAATSHRKDM4ETDP1ALDH1A1 | |
| SCHEMBL437657 | 0.88 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL1667267 | 0.88 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL16504610 | 0.88 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL8520641 | 0.88 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL18260684 | 0.88 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL17257833 | 0.88 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL5488034 | 0.88 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL5482072 | 0.88 | ALDH1A1 (0.32) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914169-A3 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 2002-08-28 | — | — | EP | claimed |
| EP-0914169-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1999-05-12 | — | — | EP | claimed |
| WO-1998053862-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1998-12-03 | — | — | WO | claimed |
| EP-0914169-A3 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-0914169-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998053862-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1998-12-03 | — | — | WO | disclosed |