Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177068 | 0.85 | ESR1 (0.41) | ESR1ESR2ADORA2AADORA1RAPGEF4 | |
| SCHEMBL8062818 | 0.84 | PTGS1 (0.37) | ESR1ESR2DAOLMNAHTT | |
| SCHEMBL30231281 | 0.82 | ESR1 (0.47) | ESR1ESR2DAONR3C2TAAR1 | |
| SCHEMBL6547407 | 0.82 | ESR1 (0.47) | ESR1ESR2DAONR3C2TAAR1 | |
| SCHEMBL8072351 | 0.81 | PTGS1 (0.39) | ESR1ESR2DAOLMNAHTT | |
| SCHEMBL29597103 | 0.79 | PTGS1 (0.45) | ESR1ESR2DAOLMNAHTT | |
| SCHEMBL311370 | 0.79 | PTGS1 (0.45) | ESR1ESR2DAOLMNAHTT | |
| SCHEMBL29380988 | 0.79 | PTGS1 (0.45) | ESR1ESR2DAOLMNAHTT | |
| SCHEMBL1803036 | 0.79 | POLB (0.46) | TAAR1ABCB1HTT | |
| SCHEMBL11897181 | 0.79 | FFAR1 (0.38) | FFAR1TAAR1HTR7LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859302-A | Processes employing reusable aluminum catalysts | ALBEMARLE CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |