SCHEMBL8467313

SCHEMBL8467313

Cc1ccc(OP(=O)(O)Oc2ccc(C)cc2C)c(C)c1.Nc1nc(N)nc(N)n1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KMT2A Q03164 1/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.36
POLB P06746 2/20 0.36
RXFP1 Q9HBX9 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
S1PR4 O95977 1/20 0.35
GAA P10253 1/20 0.35
DHFR P00374 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497308 0.88 HPGD (0.45) HPGDRAB9ATP53KMT2ALMNA
SCHEMBL5514869 0.81 CYP3A4 (0.48) HPGDKMT2ALMNACYP3A4GPR84
SCHEMBL5597453 0.81 TDP1 (0.46) HPGDRAB9ANPC1TP53HSD17B10
SCHEMBL10983224 0.81 HPGD (0.43) HPGDRAB9AKMT2ALMNAMAPT
SCHEMBL7918907 0.78 HPGD (0.51) HPGDKMT2ALMNAALDH1A1GPR84
SCHEMBL7640515 0.78 HPGD (0.41) HPGDRAB9ANPC1TP53HSD17B10
SCHEMBL109597 0.78 INPPL1 (0.52) HPGDTP53LMNAPOLB
SCHEMBL4131348 0.76 HPGD (0.44) HPGDRAB9ANPC1TP53HSD17B10
SCHEMBL27559347 0.76 INPPL1 (0.50) HPGDTP53LMNAPOLB
SCHEMBL30422472 0.75 MAPT (0.58) HPGDTP53KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5936048-A Method for preparing modified resins and their applications MITSUI CHEMICALS, INC. (JP) 1999-08-10 US disclosed
US-5869184-A RESIN RAW MATERIALS FOR PAINTS, ADHESIVES MITSUI TOATSU CHEMICALS, INC. (JP) 1999-02-09 US disclosed
EP-0698620-B1 Method for preparing modified resins and their applications MITSUI CHEMICALS INC (JP) 1998-12-09 EP disclosed
US-5792814-A REACTING A RESIN WITH A 5-((4,6-DIAMINO-S-TRIAZIN-2-YL)-NORBORN-2-ENE AND REACTING WITH AN EPOXIDE; FIREPROOFING; MOLDING MATERIALS MITSUI CHEMICALS, INC. (JP) 1998-08-11 US disclosed
US-5744504-A AMINO RESIN; THERMOSETTING MOLDING MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-04-28 US disclosed
US-5674947-A HEATING RESIN WITH FUNCTIONALIZED NORBORNENE COMPOUND IN ABSENCE OF REACTION CATALYST OR INITIATOR MITSUI TOATSU CHEMICALS, INC. (JP) 1997-10-07 US disclosed
US-5648446-A ADHESIVES, FIREPROOFING, HEAT RESISTANCE IN RESINS FOR MOLDING MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
US-5646240-A THERMOSETTING MOLDING COMPOSITIONS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-08 US disclosed
US-5596039-A FLAME RETARDERS, HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-21 US disclosed
US-5569726-A USEFUL IN FLAME-RETARDING, THERMAL STABILIZATION AND COMPATIBILIZATION OF RESINS AND IN THERMOSETTING MOLDING COMPOSITIONS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-10-29 US disclosed
US-5545702-A THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-13 US disclosed
US-5536795-A ADHESIVES AND PAINTS AND FIREPROOFING THERMOSETTING RESINS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-16 US disclosed
EP-0698620-A1 Method for preparing modified resins and their applications MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-02-28 EP disclosed
US-5480947-A N-METHYLOL DIGUANAMINES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
EP-0612797-A2 Modification method of resins MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-08-31 EP disclosed