SCHEMBL8467663

SCHEMBL8467663

FC(F)(F)Oc1ccc(C2CC=C(CCCCCCC(C3CCCCC3)C3CCCCC3)CC2)cc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.35
EPHX2 P34913 2/20 0.35
GABBR2 O75899 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
F2R P25116 2/20 0.31
GALR2 O43603 1/20 0.31
GALR1 P47211 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8029523 0.79 SCN9A (0.40) EPHX1EPHX2GALR2GALR1KDM4E
SCHEMBL8029152 0.78 SCN9A (0.41) EPHX1EPHX2KDM4EALDH1A1POLB
SCHEMBL8047765 0.77 L3MBTL1 (0.38) L3MBTL1
SCHEMBL8050501 0.76 L3MBTL1 (0.37) EPHX1EPHX2MEN1KMT2AL3MBTL1
SCHEMBL8041004 0.74 SCN9A (0.42) EPHX1EPHX2L3MBTL1KDM4EALDH1A1
SCHEMBL8049001 0.73 L3MBTL1 (0.40) EPHX2L3MBTL1
SCHEMBL9808476 0.73 GALR2 (0.36) EPHX1EPHX2GALR2GALR1KDM4E
SCHEMBL9808590 0.73 GALR2 (0.36) EPHX1EPHX2GALR2GALR1KDM4E
SCHEMBL8052555 0.72 TEAD1 (0.35) L3MBTL1ALDH1A1
SCHEMBL8464560 0.72 KDM1A (0.38) EPHX2MEN1KMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675187-B1 Liquid crystalline compounds and liquid crystal composition CHISSO CORP (JP) 1999-09-15 EP disclosed
EP-0675187-A2 Liquid crystalline compounds and liquid crystal composition Chisso Corporation (JP) 1995-10-04 EP disclosed