SCHEMBL8467718

SCHEMBL8467718

CCCCCCCCCCC(OC(=O)c1ccccc1C(=O)OC(CCCCCCCCCC)C(CCCCCCC)CCCCCCCC)C(CCCCCCC)CCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.62
PRSS1 P07477 1/20 0.56
PRSS2 P07478 1/20 0.56
PRSS3 P35030 1/20 0.56
TSHR P16473 6/20 0.54
LMNA P02545 3/20 0.54
CYP3A4 P08684 4/20 0.51
MAPK1 P28482 2/20 0.51
TP53 P04637 1/20 0.51
L3MBTL1 Q9Y468 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
CA2 P00918 1/20 0.48
KDM4E B2RXH2 3/20 0.44
HSD17B10 Q99714 2/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
NR1I2 O75469 1/20 0.42
CHRM2 P08172 1/20 0.42
ADRA2A P08913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8465141 1.00 ALDH1A1 (0.62) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL8466686 1.00 ALDH1A1 (0.62) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL8466736 1.00 ALDH1A1 (0.62) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL9834750 0.94 ALDH1A1 (0.71) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL22833304 0.94 ALDH1A1 (0.71) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL1789449 0.94 ALDH1A1 (0.59) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL27774141 0.90 ALDH1A1 (0.66) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL1789451 0.89 ALDH1A1 (0.68) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL2351531 0.88 ALDH1A1 (0.67) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL28429697 0.88 ALDH1A1 (0.67) ALDH1A1PRSS1PRSS2PRSS3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260650-A Plastic composition containing at least one metal pigment, method for the production thereof and use thereof 埃卡特有限公司 2022-11-01 CN disclosed
CN-109777177-B Water-based compositions with stain resistance 宣伟投资管理有限公司 2022-03-15 CN disclosed
CN-112236487-A Water-based compositions with long-term gloss retention 宣伟投资管理有限公司 2021-01-15 CN disclosed
US-5922900-A CATALYST COMPRISING POLYSILOXANE MODIFIED WITH SULFONIC ACID GROUPS AND SOLUBLE ALUMINUM, TITANIUM OR ZIRCONIUM COMPOUND DEGUSSA AKTIENGESELLSCHAFT (DE) 1999-07-13 US disclosed
EP-0465648-B1 LAMINATED RESIN FILM HAVING METALLIC APPEARANCE NIPPON CARBIDE KOGYO KK (JP) 1995-08-02 EP disclosed
US-5225267-A Polyvinyl chloride resin film with polyurethanes and metal layer and a marking film NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1993-07-06 US disclosed
EP-0465648-A1 LAMINATED RESIN FILM HAVING METALLIC APPEARANCE NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1992-01-15 EP disclosed
EP-0193346-B1 PROCESS FOR FORMING A HOT MELT COMPOSITION GENESCO INC. (US) 1991-10-23 EP disclosed
EP-0134389-B1 VINYL CHLORIDE RESIN COMPOSITION NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1988-07-27 EP disclosed
US-4670490-A CONTAINING DIESTER PLASTICIZER-MOLDING MATERIALS NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1987-06-02 US disclosed
EP-0193346-A2 Process for forming a hot melt composition GENESCO INC. (US) 1986-09-03 EP disclosed
US-4608418-A POLYURETHANES WITH PLASTICIZERS AND CHAIN EXTENDERS GENSCO INC. (US) 1986-08-26 US disclosed
EP-0134389-A2 Vinyl chloride resin composition NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1985-03-20 EP disclosed
US-4282286-A Process for making destructible marking film and method for marking NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1981-08-04 US disclosed
US-4252853-A VINYL CHLORIDE RESIN AND AN ALKYL METHACRYLATE RESIN, PLASTICIZER AND PIGMENTS NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1981-02-24 US disclosed