SCHEMBL8467738

SCHEMBL8467738

CCCCCCCCCCCCCCCCOCC(CO)OC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.75
MAPK1 P28482 1/20 0.75
PRKCA P17252 5/20 0.74
PRKCE Q02156 2/20 0.74
PRKCQ Q04759 2/20 0.74
PRKCD Q05655 2/20 0.74
LMNA P02545 3/20 0.61
ALDH1A1 P00352 1/20 0.61
S1PR1 P21453 1/20 0.54
USP2 O75604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394036 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL9010956 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL10620809 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL7416016 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL16726792 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL3763399 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL9070261 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL9787451 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL10893167 1.00 MAPT (0.75) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL14952939 0.94 PRKCA (0.67) MAPTMAPK1PRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109640951-B Preparation of microparticles of controlled size 博莱科瑞士股份有限公司 2023-08-25 CN disclosed
CN-114269367-A Therapeutic peptides 科巴公司 2022-04-01 CN disclosed
CN-110478495-A Target conjugate and its particle and preparation TARVEDA THERAPEUTICS INC 2019-11-22 CN disclosed
CN-106573077-B Targeted conjugates and particles and formulations thereof 塔弗达治疗有限公司 2019-07-30 CN disclosed
CN-110072883-A The relevant peptide of therapeutic MOTS-C 科巴公司 2019-07-30 CN disclosed
CN-104936622-A Targeted conjugates encapsulated in particles and formulations thereof BLEND THERAPEUTICS INC 2015-09-23 CN disclosed
EP-0762899-A4 STABILIZED HOMOGENOUS SUSPENSIONS AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP (US) 1999-08-18 EP disclosed
EP-0762899-A1 STABILIZED HOMOGENOUS SUSPENSIONS AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP. (US) 1997-03-19 EP disclosed
WO-1995032005-A1 STABILIZED HOMOGENOUS SUSPENSIONS AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP. (US) 1995-11-30 WO disclosed