Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834547 | 0.85 | AOC3 (0.61) | AOC3ITGB3ITGA2BALOX15PIN1 | |
| SCHEMBL29505381 | 0.84 | AOC3 (0.60) | AOC3ITGB3ITGA2BALOX15PIN1 | |
| SCHEMBL14061622 | 0.84 | AOC3 (0.60) | AOC3ITGB3ITGA2BALOX15PIN1 | |
| SCHEMBL7797432 | 0.83 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL6833682 | 0.83 | AOC3 (0.68) | AOC3ITGB3ITGA2B | |
| SCHEMBL4070429 | 0.81 | AOC3 (0.56) | AOC3ALOX15PIN1PIN4 | |
| SCHEMBL14062095 | 0.81 | AOC3 (0.59) | AOC3ITGB3ITGA2B | |
| SCHEMBL19510710 | 0.77 | AOC3 (0.53) | AOC3ITGB3ITGA2BALOX15PIN1 | |
| SCHEMBL29505424 | 0.77 | AOC3 (0.53) | AOC3ITGB3ITGA2BALOX15PIN1 | |
| SCHEMBL14061892 | 0.77 | AOC3 (0.53) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| CN-1209060-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-02-24 | — | — | CN | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |