Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972384 | 0.69 | HCAR1 (0.33) | HCAR1 | |
| SCHEMBL5267507 | 0.67 | CCND1 (0.59) | HCAR1 | |
| SCHEMBL22860429 | 0.64 | NUAK1 (0.40) | HCAR1 | |
| SCHEMBL5868591 | 0.60 | — | — | |
| SCHEMBL24618839 | 0.57 | CDK4 (0.32) | — | |
| SCHEMBL5868555 | 0.55 | — | — | |
| SCHEMBL14811013 | 0.54 | — | — | |
| SCHEMBL25421857 | 0.54 | — | — | |
| SCHEMBL25422210 | 0.54 | — | — | |
| SCHEMBL25421352 | 0.53 | HRH4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964864-A2 | PYRIDO 2,3-D] PYRIMIDINES AND 4-AMINOPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998033798-A2 | PYRIDO[2,3-D]PYRIMIDINES AND 4-AMINO-PYRIMIDINES AS INHIBITORS OF CELL PROLIFERATION | WARNER LAMBERT COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |