Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | SDCBP | O00560 | 1/20 | 0.32 |
| ▸ | SDC2 | P34741 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746785 | 1.00 | CTSC (0.39) | CTSCNPSR1HPGDSECE1CNR1 | |
| SCHEMBL28686629 | 1.00 | CTSC (0.39) | CTSCNPSR1HPGDSECE1CNR1 | |
| SCHEMBL5834459 | 0.85 | CTSC (0.35) | CTSCNPSR1ECE1ACACB | |
| SCHEMBL17209385 | 0.84 | DDOST (0.37) | CTSC | |
| SCHEMBL27581262 | 0.83 | CTSC (0.35) | CTSCNPSR1ECE1 | |
| SCHEMBL27581261 | 0.83 | CTSC (0.35) | CTSCNPSR1ECE1 | |
| SCHEMBL20385795 | 0.83 | CYP2C9 (0.43) | NPSR1HPGDSECE1CNR1CNR2 | |
| SCHEMBL19933158 | 0.83 | CYP2C9 (0.43) | NPSR1HPGDSECE1CNR1CNR2 | |
| SCHEMBL16310594 | 0.83 | CYP2C9 (0.43) | NPSR1HPGDSECE1CNR1CNR2 | |
| SCHEMBL15602576 | 0.83 | HPGDS (0.36) | NPSR1HPGDSECE1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999237-A | Nucleoside prodrug and application thereof | 润佳（苏州）医药科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020146541-A2 | TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-16 | — | — | WO | disclosed |
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |