Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960661 | 0.92 | ERN1 (0.68) | ERN1TNFRSF1A | |
| SCHEMBL29890082 | 0.80 | ERN1 (0.58) | ERN1TNFRSF1A | |
| SCHEMBL153974 | 0.80 | ERN1 (0.58) | ERN1TNFRSF1A | |
| SCHEMBL6091203 | 0.77 | ERN1 (0.57) | ERN1TNFRSF1A | |
| SCHEMBL4599426 | 0.77 | ERN1 (0.54) | ERN1 | |
| SCHEMBL6095281 | 0.76 | TNFRSF1A (0.62) | ERN1TNFRSF1A | |
| SCHEMBL6095278 | 0.76 | TNFRSF1A (0.62) | ERN1TNFRSF1A | |
| SCHEMBL12766763 | 0.75 | ERN1 (1.00) | ERN1 | |
| SCHEMBL27864586 | 0.74 | ALDH1A1 (0.66) | ERN1TNFRSF1A | |
| SCHEMBL5560733 | 0.72 | TNFRSF1A (0.57) | ERN1TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858444-A4 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0858444-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997014671-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |