SCHEMBL8469009

SCHEMBL8469009

CCCCC(CC)COP(=S)(S)S

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
TSHR P16473 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
ATM Q13315 1/20 0.43
ALDH1A1 P00352 7/20 0.42
CA2 P00918 3/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP14 P50281 1/20 0.38
RECQL P46063 1/20 0.36
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598265 0.89 CYP3A4 (0.61) CYP3A4L3MBTL1TSHRTDP1ATM
Hydrogen Sulfide SCHEMBL6902765 0.87 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL2456068 0.87 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
Ammonia Solution, Strong SCHEMBL10936576 0.87 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL3271728 0.87 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
Hydrogen Sulfide SCHEMBL6899432 0.87 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
Zinc Ion SCHEMBL2986391 0.85 CYP3A4 (0.58) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL4446173 0.85 CYP3A4 (0.58) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL284454 0.84 CYP3A4 (0.66) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL11305414 0.84 CYP3A4 (0.56) CYP3A4L3MBTL1TSHRTDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed