Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754622 | 1.00 | REN (0.42) | REN | |
| SCHEMBL8476452 | 0.91 | REN (0.45) | REN | |
| SCHEMBL4755815 | 0.91 | REN (0.45) | REN | |
| SCHEMBL4756821 | 0.89 | REN (0.40) | REN | |
| SCHEMBL8471863 | 0.89 | REN (0.40) | REN | |
| SCHEMBL8471726 | 0.86 | REN (0.41) | REN | |
| SCHEMBL4757261 | 0.84 | REN (0.41) | REN | |
| SCHEMBL8459468 | 0.84 | REN (0.41) | REN | |
| SCHEMBL4790410 | 0.81 | REN (0.42) | REN | |
| SCHEMBL8471421 | 0.81 | REN (0.42) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |