Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | F2 | P00734 | 8/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522455 | 1.00 | CA12 (0.43) | CA12CA9F2PRSS1PRSS2 | |
| SCHEMBL29543947 | 0.91 | CA12 (0.45) | CA12CA9F2PRSS1PRSS2 | |
| SCHEMBL29567304 | 0.90 | CA12 (0.43) | CA12CA9F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL29804450 | 0.89 | CA12 (0.43) | CA12CA9F2PRSS1PRSS2 | |
| SCHEMBL29566105 | 0.88 | KDM4E (0.44) | CA12CA9KDM4EALDH1A1USP2 | |
| SCHEMBL12955580 | 0.86 | F2 (0.44) | F2PRSS1PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL29692752 | 0.85 | NTMT1 (0.43) | CA12CA9F2PRSS1PRSS2 | |
| SCHEMBL30503068 | 0.85 | KDM4E (0.43) | CA12CA9KDM4EALDH1A1USP2 | |
| SCHEMBL11349320 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1USP2POLBHPGD | |
| SCHEMBL11349327 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1USP2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935802-A | Method of assaying a blood sample for prothrombin | EVANSTON NORTHWESTERN HEALTHCARE RESEARCH INSTITUTE (US) | 1999-08-10 | — | — | US | disclosed |