Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573200 | 0.89 | KMT2A (0.49) | ALDH1A1MAPTHPGDKMT2AGAA | |
| SCHEMBL15893259 | 0.85 | GAA (0.45) | ALDH1A1MAPTHPGDKMT2AGAA | |
| SCHEMBL837763 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDKMT2AGAA | |
| SCHEMBL4856528 | 0.82 | GAA (0.54) | ALDH1A1MAPTHPGDKMT2AGAA | |
| SCHEMBL6139899 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDKMT2AGAA | |
| Hydrochloric Acid SCHEMBL5595603 | 0.80 | GAA (0.52) | ALDH1A1MAPTHPGDKMT2AGAA | |
| SCHEMBL20434004 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDKMT2AGAA | |
| Hydrochloric Acid SCHEMBL6139898 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDKMT2AGAA | |
| SCHEMBL6074966 | 0.79 | GAA (0.50) | ALDH1A1MAPTHPGDKMT2AGAA | |
| SCHEMBL19264717 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789571-A4 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO INC (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0789571-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | Merck & Co., Inc. (US) | 1997-08-20 | — | — | EP | disclosed |