SCHEMBL8469144

SCHEMBL8469144

CCO[Si](CCCN)OCC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.33
CYP1A2 P05177 1/20 0.33
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469919 0.92 DNM1 (0.38) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL340450 0.78 TSHR (0.33) TSHR
SCHEMBL8470546 0.77
SCHEMBL23365031 0.76 TSHR (0.37) TSHR
SCHEMBL21838289 0.75 CYP1A2 (0.31) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL19970590 0.74 TSHR (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL23365064 0.74 TSHR (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL6899449 0.74
SCHEMBL3991107 0.72
SCHEMBL338941 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110709259-B Rubber composition 米其林集团总公司 2022-07-15 CN claimed
CN-110719934-B Functionalized ethylene and 1, 3-butadiene copolymers 米其林集团总公司 2022-06-24 CN claimed
CN-110709463-B Functionalized copolymers composed of 1, 3-dienes and olefins 米其林集团总公司 2022-04-15 CN claimed
US-11155656-B2 Functional ethylene and 1,3-butadiene copolymer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-10-26 US claimed
US-20210079135-A1 RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-03-18 US claimed
US-10899893-B2 Aminosilane-modified colloidal silica dispersion and method of manufacturing same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-26 US claimed
US-20200157268-A1 FUNCTIONAL COPOLYMER CONSISTING OF A 1,3-DIENE AND AN OLEFINE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-05-21 US claimed
US-20200140587-A1 FUNCTIONAL ETHYLENE AND 1,3-BUTADIENE COPOLYMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-05-07 US claimed
EP-3635051-A1 FUNCTIONAL ETHYLENE AND 1,3-BUTADIENE COPOLYMER Compagnie Générale des Etablissements Michelin (FR) 2020-04-15 EP claimed
EP-3634776-A1 RUBBER COMPOSITION Compagnie Générale des Etablissements Michelin (FR) 2020-04-15 EP claimed
EP-3635052-A1 FUNCTIONAL COPOLYMER CONSISTING OF A 1,3-DIENE AND AN OLEFINE Compagnie Générale des Etablissements Michelin (FR) 2020-04-15 EP claimed
CN-110719934-A Functionalized ethylene and 1, 3-butadiene copolymers 米其林集团总公司 2020-01-21 CN claimed
CN-110709259-A Rubber composition 米其林集团总公司 2020-01-17 CN claimed
CN-110709463-A Functionalized copolymers composed of 1, 3-dienes and olefins 米其林集团总公司 2020-01-17 CN claimed
WO-1999063003-A1 LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS LOCTITE CORPORATION (US) 1999-12-09 WO claimed
CN-118027546-A Rubber composition 米其林集团总公司 2024-05-14 CN disclosed
CN-112888580-B Rubber composition 米其林集团总公司 2023-11-03 CN disclosed
CN-110709463-A Functionalized copolymers composed of 1, 3-dienes and olefins 米其林集团总公司 2020-01-17 CN disclosed
CN-110709259-A Rubber composition 米其林集团总公司 2020-01-17 CN disclosed
WO-1999063003-A1 LOW-OUTGASSING, ROOM TEMPERATURE VULCANIZING SILICONE COMPOSITIONS LOCTITE CORPORATION (US) 1999-12-09 WO disclosed