Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466144 | 1.00 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL8466141 | 1.00 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL8466142 | 1.00 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL8701401 | 0.92 | TACR1 (0.65) | TACR1KCNH2 | |
| SCHEMBL8701402 | 0.92 | TACR1 (0.65) | TACR1KCNH2 | |
| SCHEMBL8701404 | 0.92 | TACR1 (0.65) | TACR1KCNH2 | |
| SCHEMBL8461878 | 0.90 | TACR1 (0.64) | TACR1KCNH2 | |
| SCHEMBL8702740 | 0.88 | TACR1 (0.61) | TACR1KCNH2 | |
| SCHEMBL8701455 | 0.88 | TACR1 (0.61) | TACR1KCNH2 | |
| SCHEMBL8462511 | 0.87 | TACR1 (0.60) | TACR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858444-A4 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0858444-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997014671-A1 | CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |