Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701401 | 1.00 | TACR1 (0.65) | TACR1KCNH2NR1I2 | |
| SCHEMBL8701402 | 1.00 | TACR1 (0.65) | TACR1KCNH2NR1I2 | |
| SCHEMBL8700926 | 0.92 | TACR1 (0.58) | TACR1KCNH2NR1I2 | |
| SCHEMBL8700928 | 0.92 | TACR1 (0.58) | TACR1KCNH2NR1I2 | |
| SCHEMBL8466144 | 0.92 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL8466142 | 0.92 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL8469168 | 0.92 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL8466141 | 0.92 | TACR1 (0.62) | TACR1KCNH2 | |
| SCHEMBL8701455 | 0.91 | TACR1 (0.61) | TACR1KCNH2NR1I2 | |
| SCHEMBL8702740 | 0.91 | TACR1 (0.61) | TACR1KCNH2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |