SCHEMBL8469310 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	LCK	P06239	15/20	0.46

▸	FGFR1	P11362	2/20	0.33

▸	S100B	P04271	1/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	MAPK1	P28482	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	HSD17B10	Q99714	1/20	0.33

▸	L3MBTL1	Q9Y468	1/20	0.33

▸	LYN	P07948	1/20	0.33

▸	BTK	Q06187	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8470401	0.93	LCK (0.52)	LCK
SCHEMBL8472491	0.88	LCK (0.44)	LCKFGFR1LYNBTK
SCHEMBL8469801	0.81	LCK (0.50)	LCK
SCHEMBL7983005	0.76	LCK (0.50)	LCK
SCHEMBL7983065	0.75	LCK (0.52)	LCK
SCHEMBL7983561	0.73	LCK (0.47)	LCK
SCHEMBL7987372	0.72	LCK (0.48)	LCKFGFR1
SCHEMBL4038275	0.72	LCK (0.40)	LCK
SCHEMBL7979958	0.72	LCK (0.56)	LCK
SCHEMBL4043849	0.71	LCK (0.43)	LCKFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999009845-A1	IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS	BRISTOL-MYERS SQUIBB COMPANY (US)	1999-03-04	—	—	WO	claimed