Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 8/20 | 0.43 |
| ▸ | PIM1 | P11309 | 5/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042263 | 0.94 | LCK (0.47) | LCKPIM1FGFR1SRC | |
| SCHEMBL4038945 | 0.83 | LCK (0.50) | LCK | |
| SCHEMBL4042434 | 0.82 | LCK (0.41) | LCKFGFR1 | |
| SCHEMBL4043255 | 0.80 | NOS1 (0.40) | LCKFGFR1PIK3CD | |
| SCHEMBL7979958 | 0.79 | LCK (0.56) | LCK | |
| SCHEMBL4036111 | 0.77 | LCK (0.42) | LCKFGFR1SRC | |
| SCHEMBL4038830 | 0.77 | LCK (0.49) | LCKFGFR1 | |
| SCHEMBL4041190 | 0.77 | LCK (0.51) | LCKFGFR1SRC | |
| SCHEMBL4044486 | 0.77 | LCK (0.38) | LCK | |
| SCHEMBL4037168 | 0.76 | MEN1 (0.44) | LCKFGFR1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | claimed |