Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386620 | 0.86 | GPR55 (0.47) | HTR2BHRH3DRD2MAOAMAOB | |
| SCHEMBL5032790 | 0.84 | HRH3 (0.55) | HTR2BHRH3KCNH2 | |
| SCHEMBL8469563 | 0.84 | HTR2B (0.47) | HTR2BHRH3KCNH2 | |
| SCHEMBL5034855 | 0.81 | HRH3 (0.55) | HRH3KCNH2 | |
| SCHEMBL5030411 | 0.80 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL5225993 | 0.79 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL5032985 | 0.78 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL1313764 | 0.77 | HRH3 (0.52) | HRH3KCNH2 | |
| SCHEMBL8470899 | 0.76 | APP (0.42) | HRH3MAOAMAOBPTGES | |
| SCHEMBL8470896 | 0.76 | APP (0.42) | HRH3MAOAMAOBPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5866577-A | AN ANTICOAGULANT AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |