Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SOD1 | P00441 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508201 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AALOX15HPGD | |
| SCHEMBL3790582 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1NR4A2MEN1KMT2A | |
| SCHEMBL19631178 | 0.76 | TSHR (0.43) | TSHRALDH1A1NR4A2MEN1KMT2A | |
| SCHEMBL28483242 | 0.75 | CYP2A6 (0.46) | ALDH1A1MEN1KMT2AALOX15HPGD | |
| SCHEMBL8462873 | 0.72 | ALDH1A1 (0.44) | TSHRALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5636326 | 0.71 | TSHR (0.39) | TSHRALDH1A1NR4A2MEN1KMT2A | |
| SCHEMBL2002259 | 0.71 | POLB (0.56) | TSHRALDH1A1NR4A2ALOX15L3MBTL1 | |
| SCHEMBL1082915 | 0.71 | MEN1 (0.69) | TSHRALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL11398854 | 0.70 | MEN1 (0.52) | TSHRALDH1A1MEN1KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL4764352 | 0.70 | TSHR (0.38) | TSHRALDH1A1NR4A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | claimed |
| JP-9143152-A | — | — | None | — | — | JP | disclosed |
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| US-5872300-A | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfanes, and 2-amino-6-chlorophenyl-isopropylsulfane | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| JP-H09143152-A | PRODUCTION OF 2-AMINO-6-CHLOROPHENYL-ALKYLSULFANE AND 2-AMINO-6-CHLOROPHENYL-ISOPROPYLSULFANE | BAYER AG | 1997-06-03 | — | — | JP | disclosed |
| EP-0775693-A1 | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfides and 2-amino-6-chlorophenyl-isopropylsulfide | BAYER AG (DE) | 1997-05-28 | — | — | EP | disclosed |
| EP-0775693-A1 | Process for the preparation of 2-amino-6-chlorophenyl-alkylsulfides and 2-amino-6-chlorophenyl-isopropylsulfide | BAYER AG (DE) | 1997-05-28 | — | — | EP | disclosed |