SCHEMBL8469646

SCHEMBL8469646

Cc1ccc(N)cc1.Cc1ccc(N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 1.00
TEAD4 Q15561 1/20 0.68
ALDH1A1 P00352 9/20 0.65
TDP1 Q9NUW8 6/20 0.65
MAPT P10636 2/20 0.65
POLB P06746 1/20 0.65
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
CYP3A4 P08684 4/20 0.50
TP53 P04637 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
TSHR P16473 1/20 0.47
ALOX15 P16050 4/20 0.45
MAPK1 P28482 3/20 0.45
THRB P10828 2/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11887 1.00
Ammonia Solution, Strong SCHEMBL4839623 0.96
Methylamine SCHEMBL11822116 0.96 ACHE (0.93) ACHETEAD4ALDH1A1TDP1MAPT
Ethane SCHEMBL7215590 0.96 ACHE (0.93) ACHETEAD4ALDH1A1TDP1MAPT
Water SCHEMBL8599810 0.96
Fluoride SCHEMBL7708424 0.96 ACHE (0.93) ACHETEAD4ALDH1A1TDP1MAPT
SCHEMBL1439188 0.96
Hydrochloric Acid SCHEMBL515756 0.96
SCHEMBL6463424 0.96
Hydrochloric Acid SCHEMBL10938359 0.96 ACHE (0.93) ACHETEAD4ALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012168470-A1 METHOD FOR THE DETERMINATION OF THE CONCENTRATION OF VITAMIN B6 IN A SAMPLE BÜHLMANN LABORATORIES AG (CH) 2012-12-13 WO claimed
CN-104593095-A High octane unleaded aviation gasoline SHELL INT RESEARCH 2015-05-06 CN disclosed
CN-104593096-A High octane unleaded aviation gasoline SHELL INT RESEARCH 2015-05-06 CN disclosed
CN-104593094-A High octane unleaded aviation gasoline SHELL INT RESEARCH 2015-05-06 CN disclosed
WO-2012168470-A1 METHOD FOR THE DETERMINATION OF THE CONCENTRATION OF VITAMIN B6 IN A SAMPLE BÜHLMANN LABORATORIES AG (CH) 2012-12-13 WO disclosed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US disclosed
US-5432283-A Substituted phenyl in 2 position; intermediates for drugs to treat hypertensive pathologies, cardiac, renal or pulmonary insufficiencies, and glaucoma SYNTHELABO (FR) 1995-07-11 US disclosed
US-5371227-A Quinoline derivatives, process for their preparation, and their therapeutic applications SYNTHELABO (FR) 1994-12-06 US disclosed