Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469678 | 0.82 | LCK (0.47) | LCK | |
| SCHEMBL7970038 | 0.80 | LCK (0.64) | LCKLYNBTK | |
| SCHEMBL7979769 | 0.74 | LCK (0.39) | LCKNPC1KMT2ARXFP1POLB | |
| SCHEMBL7970124 | 0.66 | LCK (0.72) | LCK | |
| SCHEMBL7970605 | 0.65 | KMT2A (0.42) | LCKNPC1KMT2ARXFP1POLB | |
| SCHEMBL7969605 | 0.65 | LCK (0.64) | LCKKMT2ALYNBTK | |
| SCHEMBL7970071 | 0.65 | LCK (0.72) | LCKLYNBTK | |
| SCHEMBL7982979 | 0.65 | LCK (0.79) | LCKNPC1POLBLYNBTK | |
| SCHEMBL21037121 | 0.61 | RAPGEF4 (0.55) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL13415857 | 0.60 | DUSP26 (0.62) | KMT2APOLBMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |