SCHEMBL8469769

SCHEMBL8469769

CC1=Cc2c(Cc3ccccc3)cccc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(Cc3ccccc3)cccc21)=[Si](C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.31
PTGER3 P43115 1/20 0.31
PTGER2 P43116 1/20 0.31
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8597213 0.84 GABRA1 (0.30)
SCHEMBL1238163 0.83
SCHEMBL5952760 0.82
SCHEMBL5617498 0.81
SCHEMBL6440169 0.80
SCHEMBL8150768 0.79 CSNK2A2 (0.32)
SCHEMBL1240069 0.77 PBRM1 (0.30)
SCHEMBL338922 0.77 PDCD1 (0.30)
SCHEMBL3968987 0.76
SCHEMBL3120877 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869723-A PRODUCING HIGHLY ACTIVE POLYMER WHICH DOES NOT ATTACH TO INNER WALL OF REACTOR SHOWA DENKO K.K. (JP) 1999-02-09 US disclosed
EP-0775707-A1 IONIC COMPOUNDS AND CATALYST FOR OLEFIN POLYMERIZATION USING THE COMPOUNDS SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-05-28 EP disclosed