Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27266063 | 0.81 | KMT2A (0.38) | ALDH1A1POLBRECQLEPHX1MEN1 | |
| SCHEMBL20903678 | 0.78 | EPHX1 (0.51) | EPHX1MEN1KMT2ASIGMAR1 | |
| SCHEMBL23223157 | 0.76 | EPHX1 (0.38) | ALDH1A1POLBRECQLEPHX1MEN1 | |
| SCHEMBL26022716 | 0.76 | TRPV1 (0.36) | ALDH1A1MEN1KMT2ACNR2CNR1 | |
| SCHEMBL26022715 | 0.73 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL17404926 | 0.71 | EPHX1 (0.47) | ALDH1A1EPHX1SIGMAR1 | |
| SCHEMBL17655762 | 0.71 | — | — | |
| SCHEMBL13076414 | 0.69 | EPHX1 (0.48) | ALDH1A1POLBRECQLEPHX1KMT2A | |
| SCHEMBL24444710 | 0.69 | EPHX1 (0.48) | ALDH1A1POLBRECQLEPHX1KMT2A | |
| SCHEMBL13075678 | 0.69 | EPHX1 (0.48) | ALDH1A1POLBRECQLEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870405-A1 | Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands | BIOPROJET (FR) | 2007-12-26 | — | — | EP | disclosed |