Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469793 | 0.76 | ALDH1A1 (0.39) | EPHX1ALDH1A1RAB9APOLBRECQL | |
| SCHEMBL18880075 | 0.75 | EPHX1 (0.44) | EPHX1ALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL17762579 | 0.69 | ALDH1A1 (0.49) | EPHX1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16522418 | 0.69 | SMN1; SMN2 (0.50) | EPHX1ALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL13076414 | 0.68 | EPHX1 (0.48) | EPHX1ALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL13075678 | 0.68 | EPHX1 (0.48) | EPHX1ALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL24444710 | 0.68 | EPHX1 (0.48) | EPHX1ALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL12204173 | 0.67 | SMYD3 (0.41) | EPHX1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1241744 | 0.67 | SMYD3 (0.41) | EPHX1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15014593 | 0.67 | EPHX1 (0.48) | EPHX1ALDH1A1CYP3A4CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248979-B1 | NOVEL INHIBITOR OF FLT3 KINASE AND USE THEREOF | HEFEI INST PHYSICAL SCI CAS (CN) | 2021-04-14 | — | — | EP | disclosed |