SCHEMBL8469846

SCHEMBL8469846

CCc1ccc(-c2ccc(C(=O)OCc3ccccc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.69
TDP1 Q9NUW8 3/20 0.69
SLC6A2 P23975 1/20 0.69
SLC6A3 Q01959 1/20 0.69
LMNA P02545 3/20 0.68
MAPT P10636 8/20 0.63
ALDH1A1 P00352 5/20 0.63
HPGD P15428 2/20 0.63
RAB9A P51151 5/20 0.61
GAA P10253 2/20 0.61
NPC1 O15118 4/20 0.60
MEN1 O00255 1/20 0.59
SMN1; SMN2 Q16637 4/20 0.55
KDM4E B2RXH2 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13469241 0.95 KMT2A (0.76) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL9537786 0.92 KMT2A (0.81) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL23134300 0.90 KMT2A (0.79) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL9537746 0.90 KMT2A (0.79) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL6668579 0.88 KMT2A (0.74) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL9331636 0.87 KMT2A (0.69) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL6393682 0.87 LMNA (0.90) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL29163747 0.86 KMT2A (0.79) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL312287 0.86 KMT2A (0.92) KMT2ATDP1SLC6A2SLC6A3LMNA
SCHEMBL5433051 0.86 MAPT (0.65) KMT2ATDP1SLC6A2SLC6A3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641372-B1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL UNIV KENT STATE OHIO (US) 1999-04-21 EP disclosed
EP-0582656-B1 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL UNIV KENT STATE OHIO (US) 1999-04-07 EP disclosed
US-5695682-A Liquid crystalline light modulating device and material KENT STATE UNIVERSITY (US) 1997-12-09 US disclosed
US-5691795-A Polymer stabilized liquid crystalline light modulating device and material KENT STATE UNIVERSITY (US) 1997-11-25 US disclosed
US-5437811-A Liquid crystalline light modulating device and material KENT STATE UNIVERSITY (US) 1995-08-01 US disclosed
EP-0641372-A1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL KENT STATE UNIVERSITY (US) 1995-03-08 EP disclosed
EP-0582656-A4 1994-04-13 EP disclosed
EP-0582656-A1 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL KENT STATE UNIVERSITY (US) 1994-02-16 EP disclosed
WO-1993023496-A1 LIQUID CRYSTALLINE LIGHT MODULATING DEVICE & MATERIAL KENT STATE UNIVERSITY (US) 1993-11-25 WO disclosed
WO-1992019695-A2 CRYSTALLINE LIGHT MODULATING DEVICE AND MATERIAL KENT STATE UNIVERSITY (US) 1992-11-12 WO disclosed