Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16923117 | 0.72 | CYP3A4 (0.54) | CYP3A4HSD17B10NFKB1QPCTQPCTL | |
| SCHEMBL13683147 | 0.71 | NOTUM (0.41) | CYP3A4HSD17B10NFKB1QPCTQPCTL | |
| SCHEMBL1231062 | 0.67 | CYP11B1 (0.50) | CYP3A4HSD17B10CYP19A1MAPTLMNA | |
| SCHEMBL7649005 | 0.67 | CYP3A4 (0.50) | CYP3A4HSD17B10CYP19A1MAPTLMNA | |
| SCHEMBL22366437 | 0.67 | CYP3A4 (0.51) | CYP3A4CYP19A1MAPTLMNAENPP2 | |
| Bromide SCHEMBL28821466 | 0.65 | CYP11B1 (0.49) | CYP3A4HSD17B10MAPTLMNAENPP2 | |
| Bromide SCHEMBL12481601 | 0.65 | CYP11B1 (0.49) | CYP3A4HSD17B10MAPTLMNAENPP2 | |
| Silver SCHEMBL28021712 | 0.65 | CYP11B1 (0.49) | CYP3A4HSD17B10MAPTLMNAENPP2 | |
| Hydrochloric Acid SCHEMBL28521741 | 0.65 | CYP3A4 (0.48) | CYP3A4HSD17B10CYP19A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL5168891 | 0.65 | CYP11B1 (0.49) | CYP3A4HSD17B10MAPTLMNAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |