SCHEMBL8470293

SCHEMBL8470293

C#CCCOC(=O)C=CC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 12/20 0.57
ALOX5 P09917 3/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ATM Q13315 1/20 0.41
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8470292 1.00 HCAR2 (0.57) HCAR2ALOX5MEN1KMT2AATM
SCHEMBL5590749 0.92 ALOX5 (0.48) HCAR2ALOX5MEN1KMT2AATM
SCHEMBL5590750 0.92 ALOX5 (0.48) HCAR2ALOX5MEN1KMT2AATM
SCHEMBL14587452 0.84 TSHR (0.47) HCAR2ALOX5MEN1KMT2AATM
SCHEMBL14587457 0.82 HCAR2 (0.50) HCAR2ALOX5MEN1KMT2AATM
SCHEMBL14619697 0.82 ALOX5 (0.49) HCAR2ALOX5MEN1KMT2AATM
SCHEMBL14587459 0.82 ALOX5 (0.43) HCAR2ALOX5MEN1KMT2AATM
SCHEMBL11045900 0.80 HCAR2 (0.74) HCAR2ATMTSHRTP53EGLN1
SCHEMBL10780616 0.80 HCAR2 (0.74) HCAR2ATMTSHRTP53EGLN1
SCHEMBL1246524 0.80 HCAR2 (0.74) HCAR2ATMTSHRTP53EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6002039-A Liquid injection molding inhibitors for curable compositions GENERAL ELECTRIC COMPANY (US) 1999-12-14 US disclosed