SCHEMBL8470296

SCHEMBL8470296

c1ccc2cc3c(cc2c1)NCS3

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.47
MAPT P10636 4/20 0.47
NOX1 Q9Y5S8 4/20 0.47
NPC1 O15118 2/20 0.47
MAPK1 P28482 2/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MEN1 O00255 7/20 0.39
KMT2A Q03164 7/20 0.39
ALDH1A1 P00352 4/20 0.39
POLB P06746 2/20 0.39
ALOX15 P16050 2/20 0.39
ALOX12 P18054 2/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
MPI P34949 1/20 0.39
CASP7 P55210 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19729091 0.78 MEN1 (0.30) GAAMEN1KMT2AALDH1A1
SCHEMBL11018306 0.77 NPC1 (0.43) MAPTNPC1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL29051623 0.77 ALDH1A1 (0.63) GAAMAPTNOX1NPC1MAPK1
Bromide SCHEMBL11683988 0.77 ALDH1A1 (0.57) GAAMAPTNOX1NPC1MAPK1
SCHEMBL10626190 0.77 NQO1 (0.37) GAAMAPTNOX1NPC1MAPK1
Hydrochloric Acid SCHEMBL9823989 0.76 NPC1 (0.42) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL22293854 0.74 NOX1 (0.61) GAAMAPTNOX1NPC1MAPK1
SCHEMBL8471051 0.73 ALDH1A1 (0.43) GAAMAPTNPC1MEN1KMT2A
SCHEMBL8472408 0.72 MEN1 (0.52) GAAMAPTNPC1MEN1KMT2A
SCHEMBL11619648 0.69 MEN1 (0.41) GAAMAPTNOX1NPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301508-B1 Method for producing a silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1994-03-23 EP claimed
EP-0301508-A2 Method for producing a silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1989-02-01 EP claimed
US-5968725-A MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-10-19 US disclosed
EP-0301508-B1 Method for producing a silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1994-03-23 EP disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
EP-0301508-A2 Method for producing a silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1989-02-01 EP disclosed