Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.40 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30381193 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL8470352 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL28571235 | 1.00 | TSHR (0.47) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL571523 | 0.97 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL1101547 | 0.97 | TSHR (0.41) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL28728010 | 0.95 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL571531 | 0.95 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6652231 | 0.89 | TSHR (0.42) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL19862 | 0.88 | TSHR (0.38) | TSHRTHRBFDPS | |
| SCHEMBL8663555 | 0.87 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344222-A1 | COSMETIC O/W EMULSIONS FOR LIGHTENING SKIN | Henkel AG & Co. KGaA (DE) | 2018-07-11 | — | — | EP | disclosed |
| EP-3344226-A1 | COSMETIC COMPOSITIONS FOR LIGHTENING THE SKIN | Henkel AG & Co. KGaA (DE) | 2018-07-11 | — | — | EP | disclosed |
| EP-3154509-B1 | COSMETIC COMPOSITIONS FOR BLEACHING THE SKIN | HENKEL AG & CO KGAA (DE) | 2018-07-04 | — | — | EP | disclosed |
| EP-3154509-A1 | COSMETIC COMPOSITIONS FOR BLEACHING THE SKIN | Henkel AG & Co. KGaA (DE) | 2017-04-19 | — | — | EP | disclosed |
| WO-2017036649-A1 | COSMETIC O/W EMULSIONS FOR ANTI-WRINKLE TREATMENT | HENKEL AG & CO. KGAA (DE) | 2017-03-09 | — | — | WO | disclosed |
| WO-2017037002-A1 | COSMETIC COMPOSITIONS FOR LIGHTENING THE SKIN | HENKEL AG & CO. KGAA (DE) | 2017-03-09 | — | — | WO | disclosed |
| WO-2017036650-A1 | COSMETIC O/W EMULSIONS FOR LIGHTENING SKIN | HENKEL AG & CO. KGAA (DE) | 2017-03-09 | — | — | WO | disclosed |
| WO-2015189047-A1 | COSMETIC COMPOSITIONS FOR BLEACHING THE SKIN | HENKEL AG & CO. KGAA (DE) | 2015-12-17 | — | — | WO | disclosed |
| US-20030223982-A1 | Use of DNA repair enzymes as MMP 1 inhibitors | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030223982-A1 | Use of DNA repair enzymes as MMP 1 inhibitors | MMP1, DNASE1, MMP9 | TSHR 4607/4885THRB 4705/4885GGPS1 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.