Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL9264527 | 1.00 | TSHR (0.48) | TSHRALDH1A1TDP1LOXLOXL3 | |
| SCHEMBL201580 | 0.91 | — | — | |
| Alcohol SCHEMBL4630505 | 0.88 | — | — | |
| Alcohol SCHEMBL15650310 | 0.88 | TSHR (0.55) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Isopropyl Alcohol SCHEMBL5702332 | 0.86 | TSHR (0.46) | TSHRALDH1A1TDP1LOXLOXL3 | |
| SCHEMBL366052 | 0.81 | — | — | |
| Acetonitrile SCHEMBL15232266 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Acetonitrile SCHEMBL368969 | 0.81 | — | — | |
| Acetonitrile SCHEMBL169615 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Acetonitrile SCHEMBL368167 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1LOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864032-A | Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides | AMERSHAM INTERNATIONAL PLC (GB) | 1999-01-26 | — | — | US | disclosed |
| US-5567811-A | Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides | AMERSHAM INTERNATIONAL PLC (GB) | 1996-10-22 | — | — | US | disclosed |