Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035740 | 1.00 | NT5E (0.41) | NT5ELMNATP53AHCYPDE4D | |
| SCHEMBL8469441 | 0.88 | AHCY (0.52) | NT5ELMNATP53AHCYPDE4D | |
| SCHEMBL9035660 | 0.88 | AHCY (0.52) | NT5ELMNATP53AHCYPDE4D | |
| SCHEMBL8469767 | 0.82 | PDE4A (0.41) | LMNATP53AHCYPDE4DSMN1; SMN2 | |
| SCHEMBL8469585 | 0.82 | PDE4A (0.41) | LMNATP53AHCYPDE4DSMN1; SMN2 | |
| SCHEMBL8165796 | 0.82 | HSP90AA1 (0.40) | NT5ELMNATP53AHCYPDE4D | |
| SCHEMBL8469418 | 0.81 | NT5E (0.39) | NT5ELMNAADORA3ADORA1HDAC6 | |
| SCHEMBL8470473 | 0.81 | NT5E (0.39) | NT5ELMNAADORA3ADORA1HDAC6 | |
| SCHEMBL9706998 | 0.80 | STING1 (0.51) | PNPPDE3AADORA3 | |
| SCHEMBL9706999 | 0.80 | STING1 (0.51) | PNPPDE3AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2960164-B2 | — | — | 1999-10-06 | — | — | JP | claimed |
| EP-0560794-B1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | IAF BIOCHEM INT (CA) | 1996-09-18 | — | — | EP | claimed |
| WO-1992008717-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1992-05-29 | — | — | WO | claimed |
| EP-0560794-B1 | SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | IAF BIOCHEM INT (CA) | 1996-09-18 | — | — | EP | disclosed |
| EP-0560794-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. | IAF BIOCHEM INT (CA) | 1993-09-22 | — | — | EP | disclosed |
| WO-1992008717-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1992-05-29 | — | — | WO | disclosed |