Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8470519

C[N+](C)(C)CCCl.C[N+](C)(C)CCOCl.[Cl-].[Cl-]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 6/20 0.38
CHRM3 known ✓ P20309 6/20 0.38
CHRM2 known ✓ P08172 5/20 0.37
CHRM5 P08912 6/20 0.38
MAPT P10636 1/20 0.38
BLM P54132 1/20 0.38
CHRM4 P08173 5/20 0.37
CHRNB2 P17787 5/20 0.34
CHRNA4 P43681 5/20 0.34
CHRNA7 P36544 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HTR1A P08908 2/20 0.34
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
PGR P06401 1/20 0.34
TBXA2R P21731 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA10 Q9GZZ6 1/20 0.34
CHRNA9 Q9UGM1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28075635 0.89 CHRM5 (0.44) CHRM5CHRM1CHRM3MAPTBLM
Hydrochloric Acid SCHEMBL692516 0.89
Hydrochloric Acid SCHEMBL6236672 0.87 CHRM5 (0.42) CHRM5CHRM1CHRM3MAPTBLM
SCHEMBL22645 0.87
Hydrochloric Acid SCHEMBL515868 0.84 CHRM5 (0.41) CHRM5CHRM1CHRM3MAPTBLM
Hydrochloric Acid SCHEMBL8996405 0.84
Bromide SCHEMBL3918164 0.84
SCHEMBL28191171 0.84
Hydrochloric Acid SCHEMBL28075634 0.84 CHRM5 (0.40) CHRM5CHRM1CHRM3MAPTBLM
Hydrochloric Acid SCHEMBL8583231 0.81 APEX1 (0.47) MAPTBLMSMN1; SMN2LMNAAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US disclosed
US-5759701-A INK JET PRINTING XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5702804-A Recording sheets XEROX CORPORATION (US) 1997-12-30 US disclosed