SCHEMBL8470535

SCHEMBL8470535

NS(=O)(=O)C1CC(=O)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8077464 0.76
SCHEMBL3139036 0.66 GAA (0.47)
SCHEMBL24635959 0.65
SCHEMBL8744503 0.65
SCHEMBL11835120 0.64 MAP3K14 (0.43)
SCHEMBL24378258 0.62
SCHEMBL24099477 0.62
SCHEMBL18289456 0.61 ITGB1 (0.40)
SCHEMBL12160740 0.61
SCHEMBL8332155 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659177-B1 4-OXO-AZETIDINE-2-SULPHONIC ACID AMIDES AND THEIR SALTS, PROCESS FOR THEIR PRODUCTION AND THEIR USE PLIVA HANDELS GMBH (DE) 1999-12-08 EP claimed
EP-0659177-B1 4-OXO-AZETIDINE-2-SULPHONIC ACID AMIDES AND THEIR SALTS, PROCESS FOR THEIR PRODUCTION AND THEIR USE PLIVA HANDELS GMBH (DE) 1999-12-08 EP disclosed
CN-1042130-C 4-oxo-azetidin-2-sulfonic-acid-amide and salt of same, preparation and application of same PLIVA HANDELS GMBH (DE) 1999-02-17 CN disclosed
CN-1035554-C 5-thia-1,4-diazabicyclo/4.2.0/octane-3,8-dioxo analogs of beta-lactam, process for the preparation thereof and the use thereof PLIVA PHARM & CHEM WORKS (HR) 1997-08-06 CN disclosed
US-5466686-A Amides of 4-oxo-azetidine-2-sulfonic acids and salts thereof, processes for their preparation and their use PLIVA AND PLIVA HANDELS GMBH (DE) 1995-11-14 US disclosed
CN-1099750-A 4-oxo-azetidin-2-sulfonic-acid-amide and salt of same, preparation and application of same PLIVA HANDELS GMBH (DE) 1995-03-08 CN disclosed
CN-1099750-A 4-oxo-azetidin-2-sulfonic-acid-amide and salt of same, preparation and application of same PLIVA HANDELS GMBH (DE) 1995-03-08 CN disclosed
CN-1097425-A Similar thing of beta-lactam and its production and use PLIVA PHARM & CHEM WORKS (HR) 1995-01-18 CN disclosed