Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065790 | 0.78 | MAP3K14 (0.40) | MAP3K14CYP19A1CRBNDDB1MEN1 | |
| SCHEMBL11047080 | 0.77 | MAP3K14 (0.43) | MAP3K14CYP19A1CRBNDDB1IDO1 | |
| SCHEMBL36369 | 0.77 | MAP3K14 (0.43) | MAP3K14CYP19A1CRBNDDB1MEN1 | |
| SCHEMBL30158537 | 0.76 | MAP3K14 (0.41) | MAP3K14CYP19A1CRBNDDB1MEN1 | |
| SCHEMBL4226226 | 0.76 | MAP3K14 (0.41) | MAP3K14CYP19A1CRBNDDB1MEN1 | |
| SCHEMBL5086277 | 0.76 | MAP3K14 (0.41) | MAP3K14CYP19A1CRBNDDB1MEN1 | |
| SCHEMBL4226223 | 0.76 | MAP3K14 (0.41) | MAP3K14CYP19A1CRBNDDB1 | |
| SCHEMBL625564 | 0.74 | MAP3K14 (0.40) | MAP3K14CYP19A1CRBNDDB1MEN1 | |
| Bicarbonate SCHEMBL28576915 | 0.72 | MAP3K14 (0.39) | MAP3K14CYP19A1CRBNDDB1MEN1 | |
| SCHEMBL3571247 | 0.70 | CYP19A1 (0.51) | CYP19A1CRBNDDB1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941834-A | DETERGENT, ANTIDEPOSIT, VISCOSITY IMPROVER FOR LUBRICATING OIL | STANDARD OIL COMPANY (US) | 1976-03-02 | — | — | US | disclosed |