Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993026 | 0.91 | ATM (0.56) | NLRP3ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11154411 | 0.88 | NLRP3 (0.49) | NLRP3ALDH1A1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL10950278 | 0.88 | NLRP3 (0.54) | NLRP3ALDH1A1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL27402352 | 0.86 | ATM (0.52) | NLRP3ALDH1A1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL3474559 | 0.85 | NLRP3 (0.52) | NLRP3ALDH1A1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL12812272 | 0.80 | POLB (0.65) | NLRP3ALDH1A1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL11414696 | 0.80 | NLRP3 (0.52) | NLRP3ALDH1A1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL11423763 | 0.80 | NLRP3 (0.52) | NLRP3ALDH1A1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL9614032 | 0.80 | ANPEP (0.47) | NLRP3ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6544554 | 0.80 | ANPEP (0.47) | NLRP3ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952264-A | APPLYING ONE OF THE FUNGUS COCHLIOBOLUS INTERMEDIUS AND CURVULARIA INTERMEDIA TO PEST GRASS IN AGRICULTURAL CROP | LOUISIANA TECH UNIVERSITY FOUNDATION, INC. | 1999-09-14 | — | — | US | disclosed |