Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264796 | 0.98 | CA2 (0.37) | CA2GAAHSD17B10MPLAMY1A | |
| SCHEMBL9350372 | 0.98 | CA2 (0.37) | CA2GAAHSD17B10MPLAMY1A | |
| SCHEMBL8761834 | 0.98 | CA2 (0.37) | CA2GAAHSD17B10MPLAMY1A | |
| SCHEMBL22609518 | 0.98 | CA2 (0.37) | CA2GAAHSD17B10MPLAMY1A | |
| SCHEMBL15311994 | 0.95 | CA2 (0.39) | CA2GAAHSD17B10MPLAMY1A | |
| SCHEMBL29975298 | 0.93 | GAA (0.39) | GAAHSD17B10MPLAMY1AALDH1A1 | |
| SCHEMBL5718625 | 0.93 | GAA (0.39) | GAAHSD17B10MPLAMY1AALDH1A1 | |
| SCHEMBL8084715 | 0.92 | GAA (0.38) | GAAHSD17B10MPLAMY1AALDH1A1 | |
| SCHEMBL8072193 | 0.92 | GAA (0.38) | GAAHSD17B10MPLAMY1AALDH1A1 | |
| SCHEMBL5718608 | 0.92 | GAA (0.38) | GAAHSD17B10MPLAMY1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998417-A | PSYCHOLOGICAL DISORDERS; ANALGESICS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-07 | — | — | US | disclosed |